I don't have Trilogy but do have Atmosphere, Omnisphere and Stylus RMX.
For the later two you have a MIDI Learn directly in the plug-in...
I don;t think Trilogy has this ability?
But, you can place the track in Latch or Touch mode, press Play and move the parameters in Trilogy. That should work in real time.
I don't have Atmosphere on my system here... So I wonder if you can access the Automation parameters from the Track Header when in Automation mode, for offline automating.